Spravato^® Therapy

Greater Houston Psychiatric Associates would like to introduce to our patients Spravato® therapy as a potential treatment option for depression. Spravato® therapy is an FDA-approved nasal spray that contains esketamine, a chemical similar to the anesthetic ketamine. This therapy has been shown to be effective in treating adults with treatment-resistant depression who have not responded well to other forms of antidepressant medication. Spravato® therapy is typically used in combination with an oral antidepressant and is administered under the supervision of a healthcare professional in a clinical setting.

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What is SPRAVATO®?
(Esketamine)

SPRAVATO® is the first FDA-approved nasal spray medication, taken with an oral antidepressant, for Adults with treatment-resistant depression (TRD) Depressive symptoms in adults with major depressive disorder (MDD) with suicidal thoughts or actions.
If taking Spravato®, do not drive, operate machinery, or do anything where you need to be completely alert after a treatment session. You will not be able to drive, so plan transportation for treatment days.
You will administer the nasal spray yourself under the supervision of a healthcare provider. You’ll be monitored for side effects for at least 2 hours after taking SPRAVATO®. Your healthcare provider will decide when you are ready to leave the healthcare setting.
You should tell your healthcare provider about all the medicines that you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. Taking SPRAVATO® with certain medicine may cause side effects. Especially tell your healthcare provider if you take central nervous system (CNS) depressants, psychostimulants, or monoamine oxidase inhibitors (MAOIs) medicines.
Because of the risks for sedation, dissociation and abuse and misuse, SPRAVATO® is only available through a restricted program called the SPRAVATO ® Risk Evaluation and Mitigation Strategy (REMS) Program.

Getting Started

Greater Houston Psychiatric Associates is a certified SPRAVATO® REMS treatment center. Spravato®/ Esketamine Nasal Spray is a treatment that involves the administration of Spravato®/ Esketamine by a nasal spray under the direct supervision of a trained mental health care provied followed by a 2 hour monitoring period in a healthcare setting. This required monitoring is part of the Spravato® REMS program due to the potential serious side effects including sedation, possible dissociation and misuse of abuse.

For more information or to schedule an assessment, call our Spravato® Coordinator, 713-346-1548.